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Article

Polymorphisms and mutations of ACE2 and TMPRSS2 genes are associated with COVID-19: a systematic review.

European journal of medical research - 22 Feb 2022

Li Jingwei, Wang Yali, Liu Yong, Zhang Ziqu, Zhai Yuyun, Dai Yan, Wu Zijian, Nie Xiang, Du Lunfei

Abstract excerpt

OBJECTIVE: To determine the effect of polymorphisms and mutations in angiotensin-converting enzyme 2 (ACE2) and Type 2 transmembrane serine proteases (TMPRSS2) genes on susceptibility to corona virus disease 2019 (COVID-19) and patient prognosis. INTRODUCTION: From December 2019 to the current time, an outbreak of epidemic of COVID-19, characterized by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...

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Identifiers

PMID: 35193695
DOI: 10.1186/s40001-022-00647-6
PMCID: PMC8861605

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