Genetic risk, lifestyle adherence, and risk of developing hyperuricaemia in a Japanese population.

doi:10.1093/rheumatology/keae492

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Article

Genetic risk, lifestyle adherence, and risk of developing hyperuricaemia in a Japanese population.

Rheumatology (Oxford, England) - 1 May 2025

Takase Masato, Nakaya Naoki, Nakamura Tomohiro, Kogure Mana, Hatanaka Rieko, Nakaya Kumi, Chiba Ippei, Tokioka Sayuri, Kanno Ikumi, Nochioka Kotaro, Tsuchiya Naho, Hirata Takumi, Narita Akira, Obara Taku, Ishikuro Mami, Ohseto Hisashi, Uruno Akira, Kobayashi Tomoko, Kodama Eiichi N, Hamanaka Yohei, Orui Masatsugu, Ogishima Soichi, Nagaie Satoshi, Fuse Nobuo, Sugawara Junichi, Kuriyama Shinichi, Matsuda Koichi, Izumi Yoko, Kinoshita Kengo, Tamiya Gen, Hozawa Atsushi, Yamamoto Masayuki

Abstract excerpt

OBJECTIVE: The objective of this study was to investigate the inter-relationships among genetic risk, adherence to a healthy lifestyle, and susceptibility to hyperuricaemia. METHODS: This prospective cohort study was conducted with 7241 hyperuricaemia-free individuals aged ≥20 years from the Tohoku Medical Megabank Community-based cohort study. A comprehensive lifestyle score included assessment of BMI, smoking,...

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PMID: 39271169
DOI: 10.1093/rheumatology/keae492
PMCID: PMC12048061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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