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Article

Omega-3 Polyunsaturated Fatty Acids as a Protective Factor for Myopia.

American journal of ophthalmology - 1 Dec 2024

Xue Can Can, Li Hengtong, Dong Xing-Xuan, Yu Marco, Soh Zhi Da, Chong Crystal Chun Yuen, Jiang Chen, Choquet Helene, Zebardast Nazlee, Zekavat Seyedeh Maryam, Hysi Pirro G, Saw Seang Mei, Fan Qiao, Tham Yih-Chung, Pan Chen-Wei, Cheng Ching-Yu

Abstract excerpt

PURPOSE: Animal models suggest omega-3 polyunsaturated fatty acids (PUFAs) may protect against myopia by modulating choroidal blood perfusion, but clinical evidence is scarce and mixed. We aimed to determine the causality between omega-3 PUFAs and myopia using Mendelian randomization (MR) analysis. DESIGN: Two-sample MR analysis. METHODS: Exposures are genetically predicted plasma levels of 18 fatty acid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39244001
DOI: 10.1016/j.ajo.2024.08.041
PMCID: PMC11606739

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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