Article
TRPV1 corneal neuralgia mutation: Enhanced pH response, bradykinin sensitization, and capsaicin desensitization.
Proceedings of the National Academy of Sciences of the United States of America - 10 Sept 2024
Gualdani Roberta, Barbeau Solène, Yuan Jun-Hui, Jacobs Deborah S, Gailly Philippe, Dib-Hajj Sulayman D, Waxman Stephen G
Abstract excerpt
The factors that contribute to pain after nerve injury remain incompletely understood. Laser-assisted in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) are common surgical techniques to correct refractive errors. After LASIK or PRK, a subset of patients suffers intense and persistent pain, of unknown origin, described by patients as feeling like shards of glass in their eye. Here, we evaluated...
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