Article
Evolution of a bistable genetic system in fluctuating and nonfluctuating environments.
Proceedings of the National Academy of Sciences of the United States of America - 3 Sept 2024
Fernández-Fernández Rocío, Olivenza David R, Weyer Esther, Singh Abhyudai, Casadesús Josep, Sánchez-Romero María Antonia
Abstract excerpt
Epigenetic mechanisms can generate bacterial lineages capable of spontaneously switching between distinct phenotypes. Currently, mathematical models and simulations propose epigenetic switches as a mechanism of adaptation to deal with fluctuating environments. However, bacterial evolution experiments for testing these predictions are lacking. Here, we exploit an epigenetic switch in Salmonella enterica, the opvAB...
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