Article
MARVEL-minimising the emergence and dissemination of HIV-1 drug resistance in Portuguese-speaking African Countries (PALOP): low-cost portable NGS platform for HIV-1 surveillance in Africa.
BMC infectious diseases - 29 Aug 2024
Sebastião Cruz S, Pingarilho Marta, Bathy Jamila, Bonfim Elizângela, Toancha Katia, Miranda Mafalda N S, Martins M Rosário O, Gomes Perpetua, Lázaro Lazismino, Pina-Araujo Isabel, Nhampossa Tacilta, Leal Silvania, Abecasis Ana B, Pimentel Victor
Abstract excerpt
BACKGROUND: HIV-1 infections remain a global public health concern. Scaled-up antiretroviral treatment (ART) is crucial for reducing morbidity and mortality related to HIV/AIDS. The emergence of drug-resistance mutations (DRMs) compromises viral suppression and contributes to the continued HIV-1 transmission. Several reports indicate a recent increase in acquired (ADR) and transmitted (TDR) drug resistance in...
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