Article
XRCC1 codon 399Gln polymorphism is associated with radiotherapy-induced acute dermatitis and mucositis in nasopharyngeal carcinoma patients.
Radiation oncology (London, England) - 1 Feb 2013
Li Haijun, You Yanjie, Lin Canfeng, Zheng Mingzhang, Hong Chaoqun, Chen Jiongyu, Li Derui, Au William W, Chen Zhijian
Abstract excerpt
BACKGROUND: To evaluate the association between single nucleotide polymorphisms (SNPs) at the 194 and 399 codons of XRCC1, and the risk of severe acute skin and oral mucosa reactions in nasopharyngeal carcinoma patients in China. METHODS: 114 patients with nasopharyngeal carcinoma were sequentially recruited in this study. Heparinized peripheral blood samples were taken for SNPs analysis before the start of...
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