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Article

Identification of KSR2 Variants in Pediatric Patients with Severe Early-Onset Obesity from Qatar.

Genes - 23 Jul 2024

Abu-Rub Lubna I, Al-Barazenji Tara, Abiib Sumaya, Hammad Ayat S, Abbas Alaa, Hussain Khalid, Al-Shafai Mashael

Abstract excerpt

The kinase suppressor of Ras 2 (KSR2) gene is associated with monogenic obesity, and loss-of-function variants in KSR2 have been identified in individuals with severe early-onset obesity. This study investigated KSR2 variants in 9 pediatric patients with severe early-onset obesity in Qatar using whole genome sequencing among a cohort of 240 individuals. We focused on KSR2 variants with a minor allele frequency...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39202327
DOI: 10.3390/genes15080966
PMCID: PMC11353872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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