Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pitfalls When Determining HNA-1 Genotypes and Finding Novel Alleles.

International journal of molecular sciences - 22 Aug 2024

Kløve-Mogensen Kirstine, Browne Tom, Haunstrup Thure Mors, Steffensen Rudi

Abstract excerpt

Genetic variation in the FCGR3B gene is responsible for different variants of human neutrophil antigen 1 (HNA-1). Laboratory techniques currently utilized for routine HNA-1 genotyping, predominantly PCR-sequence-specific primer (PCR-SSP) and PCR-sequence-based typing (PCR-SBT), lack specificity for FCGR3B. This study compares the capabilities and limitations of existing technologies including an in-house TaqMan...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Genotyping Techniques
Share to GPI-Linked Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isoantigens

Share to Multiplex Polymerase Chain Reaction

Share to Nanopore Sequencing

Share to Polymerase Chain Reaction

Share to Receptors, IgG

Source

Open in PubMed Open full text

Identifiers

PMID: 39201813
DOI: 10.3390/ijms25169127
PMCID: PMC11354314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pitfalls When Determining HNA-1 Genotypes and Finding Novel Alleles.PMID 39201813Read ↗

Frequencies of HNA-1, HNA-3, HNA-4, and HNA-5 in the Danish and Zambian populations determined using a novel TaqMan real time polymerase chain reaction method.Semantic proximity Read ↗

Determination of human neutrophil antigen-1, -3, -4 and -5 allele frequencies in English Caucasoid blood donors using a multiplex fluorescent DNA-based assay.Semantic proximity Read ↗

Assessing high-resolution melt curve analysis for accurate detection of gene variants in complex DNA fragments.Semantic proximity Read ↗

A comparison of assays for accurate copy number measurement of the low-affinity Fc gamma receptor genes FCGR3A and FCGR3B.Semantic proximity Read ↗

Determination of neutrophil antigen HNA-3a and HNA-3b genotype frequencies in six racial groups by high-throughput 5' exonuclease assay.Semantic proximity Read ↗

An integrated approach for measuring copy number variation at the FCGR3 (CD16) locus.Semantic proximity Read ↗

Allelic Discrimination by TaqMan-PCR for Genotyping of Human Neutrophil Antigens.Semantic proximity Read ↗

Assay-dependent discordance in detecting a rare HLA-DPB1 allele: Long-range PCR vs. hybrid capture NGS.Semantic proximity Read ↗

Nobody Is Perfect: Comparison of the Accuracy of PCR-RFLP and KASP™ Method for Genotyping. ADH1B and FTO Polymorphisms as Examples.Semantic proximity Read ↗

Detection of genotyping errors by Hardy-Weinberg equilibrium testing.Semantic proximity Read ↗

Locked nucleic acid (LNA) single nucleotide polymorphism (SNP) genotype analysis and validation using real-time PCR.Semantic proximity Read ↗

Detection of interferon alpha and beta receptor subunit 1 (IFNAR1) loss-of-function Glu386∗ variant by tri-allelic genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.