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Article

Migraine: Genetic Variants and Clinical Phenotypes.

Current medicinal chemistry - 1 Jan 2019

Rainero Innocenzo, Vacca Alessandro, Govone Flora, Gai Annalisa, Pinessi Lorenzo, Rubino Elisa

Abstract excerpt

Migraine is a common, chronic neurovascular disorder caused by a complex interaction between genetic and environmental risk factors. In the last two decades, molecular genetics of migraine have been intensively investigated. In a few cases, migraine is transmitted as a monogenic disorder, and the disease phenotype cosegregates with mutations in different genes like CACNA1A, ATP1A2, SCN1A, KCNK18, and NOTCH3. In...

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Identifiers

PMID: 30027842
DOI: 10.2174/0929867325666180719120215

Genes

KCNK18
MTHFR
NOTCH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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