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Article

ERBB2/ ERBB3-mutated S100/ SOX10-positive unclassified high-grade uterine sarcoma: first detailed description of a novel entity.

Virchows Archiv : an international journal of pathology - 1 Nov 2024

Agaimy Abbas, Dermawan Josephine K, Haller Florian, Semrau Sabine, Meidenbauer Norbert, Stoehr Robert, Lax Sigurd, Hartmann Arndt, Zou Ying S, Xing Deyin, Tögel Lars, Gross John M, Michal Michael

Abstract excerpt

With the increasing use of innovative next generation sequencing (NGS) platforms in routine diagnostic and research settings, the genetic landscape of uterine sarcomas has been dynamically evolving during the last two decades. Notably, the majority of recently recognized genotypes in uterine sarcomas represent gene fusions, while recurrent oncogene mutations of diagnostic and/ or therapeutic value have been rare....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39196362
DOI: 10.1007/s00428-024-03908-3
PMCID: PMC11564289

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