Article
Cardiovascular risk in ANCA-associated vasculitis: Monocyte phenotyping reveals distinctive signatures between serological subsets.
Atherosclerosis - 1 Oct 2024
Vegting Yosta, Hanford Katie Ml, Jongejan Aldo, Gajadin Gayle Rs, Versloot Miranda, van der Bom-Baylon Nelly D, Dekker Tamara, Penne E Lars, van der Heijden Joost W, Houben Eline, Bemelman Frederike J, Neele Annette E, Moerland Perry D, Vogt Liffert, Kroon Jeffrey, Hilhorst Marc L
Abstract excerpt
BACKGROUND AND AIMS: Anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides (AAV) is associated with an increased cardiovascular risk, particularly the myeloperoxidase AAV serotype (MPO-AAV). Distinct alterations in monocyte phenotypes may cause accelerated atherosclerotic disease in AAV. METHODS: A cohort including 43 AAV patients and 19 healthy controls was included for downstream analyses....
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