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Aging promotes accumulation of senescent and multiciliated cells in human endometrial epithelium

1 Jan 2024

Abstract excerpt

STUDY QUESTION: What changes occur in the endometrium during aging, and do they impact fertility? SUMMARY ANSWER: Both the transcriptome and cellular composition of endometrial samples from women of advanced maternal age (AMA) are significantly different from that of samples from young women, suggesting specific changes in epithelial cells that may affect endometrial receptivity. WHAT IS KNOWN ALREADY: Aging is...

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Endometriosis Research and Treatment
Gynecological conditions and treatments
Reproductive System and Pregnancy

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39185250
DOI: 10.1093/hropen/hoae048

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