Article
Facilitated cascade testing (FaCT): a randomized controlled trial.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 May 2021
Nitecki Roni, Moss Haley A, Watson Catherine H, Urbauer Diana L, Melamed Alexander, Lu Karen H, Lipkin Steven M, Offit Kenneth, Rauh-Hain Jose Alejandro, Frey Melissa K
Abstract excerpt
BACKGROUND: Identifying mutation-carrying relatives of patients with hereditary cancer syndromes via cascade testing is an underused first step in primary cancer prevention. A feasibility study of facilitated genetic testing of at-risk relatives of patients with a known pathogenic mutation demonstrated encouraging uptake of cascade testing. PRIMARY OBJECTIVE: Our primary objective is to compare the proportion of...
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