Article
Brain MRI in patients with V30M hereditary transthyretin amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Dec 2024
Sousa Luísa, Pinto Catarina, Azevedo Ana, Igreja Liliana, Marta Ana, Fernandes Joana, Oliveira Pedro, Cardoso Márcio, Alves Cristina, Silva Ana Martins da, Mendonça Pinto Miguel, Sousa Ana Paula, Coelho Teresa, Taipa Ricardo
Abstract excerpt
BACKGROUND: Central nervous system dysfunction is common in longstanding hereditary transthyretin amyloidosis (ATTRv) caused by the V30M (p.V50M) mutation. Neuropathology studies show leptomeningeal amyloid deposition and cerebral amyloid angiopathy (CAA). Brain MRI is widely used in the assessment of Aβ associated CAA but there are no systematic studies with brain MRI in ATTRv amyloidosis. METHODS: we performed...
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