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Circum-Mediterranean influence in the Y-chromosome lineages associated with prostate cancer in Mexican men: A Converso heritage founder effect?

PloS one - 1 Jan 2024

Álvarez-Topete Esmeralda, Torres-Sánchez Luisa E, Hernández-Tobías Esther A, Véliz David, Hernández-Pérez Jesús G, de Lourdes López-González Ma, Meraz-Ríos Marco Antonio, Gómez Rocío

Abstract excerpt

Prostate cancer is the second most common neoplasia amongst men worldwide. Hereditary susceptibility and ancestral heritage are well-established risk factors that explain the disparity trends across different ethnicities, populations, and regions even within the same country. The Y-chromosome has been considered a prototype biomarker for male health. African, European, Middle Eastern, and Hispanic ancestries...

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PMID: 39150969
DOI: 10.1371/journal.pone.0308092
PMCID: PMC11329122

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