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Identification of gene targets that potentiate the action of rifampicin on Mycobacterium bovis BCG.

Microbiology (Reading, England) - 1 Aug 2024

Chand Pooja, Mendum Tom A, Butler Rachel E, Hingley-Wilson Suzanne M, Stewart Graham R

Abstract excerpt

Tuberculosis (TB) caused by bacteria of the Mycobacterium tuberculosis complex remains one of the most important infectious diseases of mankind. Rifampicin is a first line drug used in multi-drug treatment of TB, however, the necessary duration of treatment with these drugs is long and development of resistance is an increasing impediment to treatment programmes. As a result, there is a requirement for research...

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Identifiers

PMID: 39150447
DOI: 10.1099/mic.0.001488
PMCID: PMC11329110

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