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Genomic patterns of somatic mutations provide new prognostic, therapeutic, and biological insights in cancer.

Cell genomics - 14 Aug 2024

Tseitline Dana, Cohen Yuval, Adar Sheera

Abstract excerpt

The mutational landscape of an individual's cancer can inform on its molecular state and be used as prognostic and therapeutic markers. The study by Barbour et al.1 analyzes mutational patterns in bladder cancer samples to uncover new biological insights into the ERCC2 gene function and develop new predictive prognostic tools.

Topics

Humans
Mutation
Prognosis
Urinary Bladder Neoplasms
Genomics
Xeroderma Pigmentosum Group D Protein
Neoplasms
Biomarkers, Tumor

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39146802
DOI: 10.1016/j.xgen.2024.100635
PMCID: PMC11406164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Genomic patterns of somatic mutations provide new prognostic, therapeutic, and biological insights in cancer.PMID 39146802Read ↗

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