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Article

Exploring the Germline Genetics of In Situ and Invasive Cutaneous Melanoma: A Genome-Wide Association Study Meta-Analysis.

JAMA dermatology - 1 Sept 2024

Ingold Nathan, Seviiri Mathias, Ong Jue Sheng, Neale Rachel E, Pandeya Nirmala, Whiteman David C, Olsen Catherine M, Martin Nicholas G, Duffy David L, Khosrotehrani Kiarash, Hayward Nicholas, Montgomery Grant W, MacGregor Stuart, Law Matthew H

Abstract excerpt

Importance: It is unknown whether germline genetic factors influence in situ melanoma risk differently than invasive melanoma risk. Objective: To determine whether differences in risk of in situ melanoma and invasive melanoma are heritable. Design, Setting, and Participants: Three genome-wide association study meta-analyses were conducted of in situ melanoma vs controls, invasive melanoma vs controls, and in situ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39141363
DOI: 10.1001/jamadermatol.2024.2601
PMCID: PMC11325244

Genes

KLF4
MC1R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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