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Revealing of TLR-9 gene polymorphisms by qPCR HRM technique and their influence on TLR-9 serum level in acute myeloid leukemia patients: Case-control study.

Cytokine - 1 Oct 2024

Qasim Mohammed Maryam, Hussein Alwan Ali, Amer Almukhtar Asmaa, Kareem Aneed Al-Saedi Mohanad

Abstract excerpt

Acute myeloid leukemia (AML) is one of the most common and fatal malignancies that affect adults, which can quickly become aggressive if left untreated, and leukemia cells invade the bone marrow. TLR-9 is an innate immune cell receptor sensitive to various PAMPs and encoded by the TLR-9 gene. As is often known, genetic polymorphisms in any gene can help the development of the disease, and these three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39133967
DOI: 10.1016/j.cyto.2024.156730

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