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Single-nuclei sequencing of uterine serous carcinoma reveals racial differences in immune signaling

12 Aug 2024

Abstract excerpt

Significant racial disparities exist between Black and White patients with uterine serous carcinoma (USC). While the reasons for these disparities are unclear, several studies have demonstrated significantly different rates of driver mutations between racial groups, including TP53. However, limited research has investigated the transcriptional differences of tumors or the composition of the tumor microenvironment...

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PMID: 39133838
DOI: 10.1073/pnas.2402998121

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