Integrated single‐cell RNA sequencing and spatial transcriptomics analysis reveals the tumour microenvironment in patients with endometrial cancer responding to anti‐PD‐1 treatment

Abstract excerpt

Dear Editor: The response of patients with endometrial cancer (EC) to anti-PD-1 therapy varies.1 Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics analysis were used for identifying specific immune cell populations that might exert a vital role in determining the sensitivity to anti-PD-1 therapy in EC. The quantities and activities of CD8 cytotoxic cells and Tregs were abnormal in non-responders...

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