Clinical protocol phase II study of tumor infiltrating lymphocytes in advanced tumors with alterations in the SWI/SNF complex: the TILTS study.

doi:10.1080/14796694.2024.2385287

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Article

Clinical protocol phase II study of tumor infiltrating lymphocytes in advanced tumors with alterations in the SWI/SNF complex: the TILTS study.

Future oncology (London, England) - 1 Jan 2024

Martin-Liberal Juan, Garralda Elena, García-Donas Jesús, Soto-Castillo Juan José, Mussetti Alberto, Codony Carles, Martin-Lluesma Silvia, Muñoz Susana, Galvao Vladimir, Lostes Julia, Rotxes Marta, Prat-Vidal Cristina, Palomero Jara, Muñoz Ainhoa, Moreno Rafael, García Del Muro Xavier, Sureda Anna, Alemany Ramon, Gros Alena, Piulats Josep Maria

Abstract excerpt

The SWI/SNF complex is a chromatin remodeling complex comprised by several proteins such as SMARCA4 or SMARCB1. Mutations in its components can lead to the development of aggressive rhabdoid tumors such as epithelioid sarcoma, malignant rhabdoid tumor or small cell carcinoma of the ovary hypercalcemic type, among others. These malignancies tend to affect young patients and their prognosis is poor given the lack...

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Identifiers

PMID: 39129675
DOI: 10.1080/14796694.2024.2385287
PMCID: PMC11520549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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