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Genome editing-based mutagenesis stably modifies composition of wax esters synthesized by Euglena gracilis under anaerobic conditions.

Bioresource technology - 1 Oct 2024

Nagamine Sakura, Oishi Rikuto, Ueda Mitsuhiro, Sakamoto Tatsuji, Nakazawa Masami

Abstract excerpt

Microalgal oil production represents a promising renewable biofuel source. Metabolic engineering can enhance its utility, transforming it into an improved biofuel and expanding its applications as a feedstock for commodity chemicals, thereby increasing their value in biorefineries. This study focused on anaerobic wax ester production by the microalga Euglena gracilis, aiming to develop stable mutant strains with...

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PMID: 39127356
DOI: 10.1016/j.biortech.2024.131255

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