Article
Utility of KIT Mutations in Myeloid Neoplasms Without Documented Systemic Mastocytosis to Detect Hidden Mast Cells in Bone Marrow.
Clinical lymphoma, myeloma & leukemia - 1 Nov 2024
Kim Do Hwan, Jia Fuli, Patel Keyur P, Bose Prithviraj, Wang Sa A, Bueso-Ramos Carlos, Ok Chi Young
Abstract excerpt
BACKGROUND: KIT p.D816 mutation is strongly associated with systemic mastocytosis (SM). Next-generation sequencing (NGS) is now routinely performed in almost all bone marrow sample and KIT mutations are detected from patients who are not known or suspected to have SM. Therefore, we wanted to assess if KIT mutations in this patient population are associated with unsuspected SM. METHODS: We searched NGS result in...
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