Article
JAK2-mutant clonal hematopoiesis is associated with venous thromboembolism.
Blood - 14 Nov 2024
Zon Rebecca L, Sekar Aswin, Clapham Katharine, Oren Ohad, Niroula Abhishek, Bick Alexander G, Gibson Christopher J, Griffin Gabriel, Uddin Md Mesbah, Neuberg Donna, Natarajan Pradeep, Ebert Benjamin L
Abstract excerpt
ABSTRACT: Venous thromboembolism (VTE) is common among older individuals, but provoking factors are not identified in many cases. Patients with myeloid malignancies, especially myeloproliferative neoplasms (MPNs), are at increased risk for venous thrombosis. Clonal hematopoiesis of indeterminate potential (CHIP), a precursor state to myeloid malignancies, is common among older individuals and may similarly...
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