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Distinct clinico-molecular arterial and venous thrombosis scores for myeloproliferative neoplasms risk stratification.

Leukemia - 1 Feb 2024

Pasquer Hélène, Daltro de Oliveira Rafael, Vasseur Loic, Soret-Dulphy Juliette, Maslah Nabih, Zhao Lin-Pierre, Marcault Clémence, Cazaux Marine, Gauthier Nicolas, Verger Emmanuelle, Parquet Nathalie, Vainchenker William, Raffoux Emmanuel, Ugo Valérie, Luque Paz Damien, Roy Lydia, Lambert Wayne-Corentin, Ianotto Jean-Christophe, Lippert Eric, Giraudier Stéphane, Cassinat Bruno, Kiladjian Jean-Jacques, Benajiba Lina

Abstract excerpt

Current recommended risk scores to predict thrombotic events associated with myeloproliferative neoplasms (MPN) do not discriminate between arterial and venous thrombosis despite their different physiopathology. To define novel stratification systems, we delineated a comprehensive landscape of MPN associated thrombosis across a large long-term follow-up MPN cohort. Prior arterial thrombosis, age >60 years,...

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Janus Kinase 2
Mutation
Myeloproliferative Disorders
Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Assessment

Venous Thrombosis

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PMID: 38148396
DOI: 10.1038/s41375-023-02114-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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