Article
Clonal haematopoiesis of indeterminate potential in patients with venous thromboembolism.
Journal of thrombosis and thrombolysis - 1 Aug 2023
Guillotin Florence, Mercier Éric, Fortier Mathieu, Bouvier Sylvie, Jacquet Quentin, Dallo Marine, Chéa Mathias, Bourguignon Chloé, Cochery-Nouvellon Éva, Perez-Martin Antonia, Gris Jean-Christophe
Abstract excerpt
Over the last decade, the concept of Clonal haematopoiesis of undetermined potential (CHIP) has emerged. Low frequency somatic mutations in hematopoietic cells can occur with age and might allow formation of clones in individuals with no characterized haematological pathology. These CHIP mutations are associated with an increased risk of cancer or atherothrombosis, and their prevalence are more and more studied...
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