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Processing of genomic RNAs by Dicer in bat cells limits SARS-CoV-2 replication

25 Mar 2025

Abstract excerpt

Bats are reservoirs for numerous viruses that cause serious diseases in other animals and humans. Several mechanisms are proposed to contribute to the tolerance of bats to these pathogens. This study investigates the response of bat cells to double-stranded RNA generated by SARS-CoV-2 replication. Here, we found the involvement of Dicer in the processing of viral genomic RNAs during SARS-CoV-2 infection....

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PMID: 40133950
DOI: 10.1186/s12985-025-02693-y

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