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Association of XRCC2 with breast cancer, a multi-omics analysis at genomic, transcriptomic, and epigenomic level.

Cellular and molecular biology (Noisy-le-Grand, France) - 28 Jul 2024

Gilani Naser, Ozaslan Mehmet

Abstract excerpt

One of the main causes of cancer-related mortality for women worldwide is breast cancer (BC). The XRCC2 gene, essential for DNA repair, has been implicated in cancer susceptibility. This study aims to evaluate the association between XRCC2 and BC risk. The study was conducted at Zheen International Hospital in Erbil, Iraq, between 2021 and 2024 with a total of 88 samples, including 44 paired normal and cancer...

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Breast Neoplasms
DNA-Binding Proteins
DNA Methylation
Epigenomics
Gene Expression Regulation, Neoplastic

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PMID: 39097872
DOI: 10.14715/cmb/2024.70.7.36

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