A comparative analysis of IDH-mutant glioma in pediatric, young adult, and older adult patients.

doi:10.1093/neuonc/noae142

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A comparative analysis of IDH-mutant glioma in pediatric, young adult, and older adult patients.

Neuro-oncology - 5 Dec 2024

Lim-Fat Mary Jane, Cotter Jennifer A, Touat Mehdi, Vogelzang Jayne, Sousa Cecilia, Pisano Will, Geduldig Jack, Bhave Varun, Driver Joseph, Kao Pei-Chi, McGovern Alana, Ma Clement, Margol Ashley S, Cole Kristina, Smith Amy, Goldman Stewart, Kaneva Kristiyana, Truong AiLien, Nazemi Kellie J, Wood Matthew D, Wright Karen D, London Wendy B, Warren Katherine E, Wen Patrick Y, Bi Wenya Linda, Alexandrescu Sanda, Reardon David A, Ligon Keith L, Yeo Kee Kiat

Abstract excerpt

BACKGROUND: The frequency and significance of IDH mutations in glioma across age groups are incompletely understood. We performed a multi-center retrospective age-stratified comparison of patients with IDH-mutant gliomas to identify age-specific differences in clinico-genomic features, treatments, and outcomes. METHODS: Clinical, histologic, and sequencing data from patients with IDH-mutant, grades 2-4 gliomas,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Brain Neoplasms

Share to Follow-Up Studies

Share to Glioma

Share to Isocitrate Dehydrogenase

Share to Prognosis

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 39082676
DOI: 10.1093/neuonc/noae142
PMCID: PMC11630535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comparative analysis of IDH-mutant glioma in pediatric, young adult, and older adult patients.PMID 39082676Read ↗

Multi-institutional study of the frequency, genomic landscape, and outcome of IDH-mutant glioma in pediatrics.Semantic proximity Read ↗

IDH-mutant gliomas in children and adolescents - from biology to clinical trialsSemantic proximity Read ↗

Treatment and outcomes of IDH1-mutant gliomas in elderly patients.Semantic proximity Read ↗

IDH mutant high-grade gliomasSemantic proximity Read ↗

Redefining Treatment Paradigms for Glioma in Adolescents and Young Adults: Population-Based Evidence for Molecular Classification.Semantic proximity Read ↗

IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group.Semantic proximity Read ↗

Incidence and Survival of IDH-Wildtype Glioblastoma and IDH-Mutant Astrocytoma by Treatment and Sex: A Regional Study in Spain (2011-2021).Semantic proximity Read ↗

Tumor-initiating genetics and therapy drive divergent molecular evolution in IDH-mutant gliomasSemantic proximity Read ↗

Contemporary prognostic signatures and refined risk stratification of gliomas: An analysis of 4400 tumors.Semantic proximity Read ↗

The Spectrum of IDH- and H3-Wildtype High-Grade Glioma Subgroups Occurring across Teenage and Young Adult Patient PopulationsSemantic proximity Read ↗

Isocitrate Dehydrogenase Mutations in Low-Grade Gliomas Correlate With Prolonged Overall Survival in Older Patients.Semantic proximity Read ↗

Updates on the WHO diagnosis of IDH-mutant glioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.