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Article

Treatment and outcomes of IDH1-mutant gliomas in elderly patients.

Journal of neurosurgery - 1 Feb 2024

Giantini-Larsen Alexandra M, Abou-Mrad Zaki, Yu Kenny K, Reiner Anne S, Bale Tejus A, Tabar Viviane, Bander Evan D

Abstract excerpt

OBJECTIVE: Isocitrate dehydrogenase (IDH) mutations in both high- and low-grade gliomas are associated with an increase in survival compared with IDH-wild-type (IDHwt) tumors. A rare and understudied population is elderly individuals, ≥ 65 years of age, who have IDH1-R132H-mutant (IDHmt) gliomas. The objective of this paper was to characterize the institutions' experience with IDHmt gliomas in a patient...

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Aged
Brain Neoplasms
Child
Glioma
Isocitrate Dehydrogenase

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Treatment Outcome

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PMID: 37877960
DOI: 10.3171/2023.6.JNS222907

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