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MAPK4 predicts poor prognosis and facilitates the proliferation and migration of glioma through the AKT / mTOR pathway

31 Mar 2023

Abstract excerpt

Abstract Background Mitogen‐activated protein kinase 4 (MAPK4) is an atypical member of the mitogen‐activated protein kinase (MAPK) family. We report here that MAPK4 is overexpressed in glioma. The clinical significance, biological roles and underlying molecular mechanisms through which MAPK4 acts in glioma remain unclear. Methods Analysis of MAPK4 expression and associated survival in glioma patients was...

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PMID: 36999945
DOI: 10.1002/cam4.5859

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