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Exploring MAP3K genes in gastric cancer: biomarkers, tumor microenvironment dynamics, and chemotherapy resistance

3 Feb 2025

Abstract excerpt

BACKGROUND: Gastric cancer (GC) presents a significant global health burden, necessitating a deeper understanding of its molecular underpinnings for improved diagnostics and therapeutics. METHODS: In this study, we investigated the expression profiles and clinical implications of MAP3K genes in GC using in silico and in vitro experiments. RESULTS: Utilizing RT-qPCR analysis, we observed significant up-regulation...

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Cancer Mechanisms and Therapy
Melanoma and MAPK Pathways
NF-κB Signaling Pathways

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39901302
DOI: 10.1186/s41065-025-00364-0

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