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Article

Low KIF4A expression is associated with gastric cancer progression and aggressive phenotypes.

Scientific reports - 6 Jun 2026

Bang Seongsik, Chae Seoung Wan, Kim Yeseul, Jee Seungyun, Park Hosub, Kim Hyunsung, Paik Seung Sam, Jang Bo Gun, Myung Jaekyung

Abstract excerpt

Kinesin family member 4A (KIF4A) regulates chromosome condensation and segregation during mitosis and is upregulated as an oncogene in various malignancies. However, its role in gastric cancer (GC) remains unclear. Therefore, this study aims to evaluate the clinicopathological and prognostic significance of KIF4A expression in GC. KIF4A protein expression was assessed via immunohistochemistry and quantified using...

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Topics

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Share to Biomarkers, Tumor
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

Share to Erb-b2 Receptor Tyrosine Kinases

Share to Gene Expression Regulation, Neoplastic

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Share to Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 42251143
DOI: 10.1038/s41598-026-56572-9
PMCID: PMC13482472

Genes

KIF4A
GC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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