Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

5 Jan 2024

Abstract excerpt

BACKGROUND: Gastric cancer (GC) is a common malignancy and a leading cause of cancer-related death with high morbidity and mortality. Methyl-CpG binding domain protein 3 (MBD3), a key epigenetic regulator, is abnormally expressed in several cancers, participating in progression and metastasis. However, the role of MBD3 in GC remains unknown. METHODS: MBD3 expression was assessed via public databases and validated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Remodeling and Cancer
Share to Epigenetics and DNA Methylation
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38178023
DOI: 10.1186/s12575-023-00228-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathwayPMID 38178023Read ↗

LncRNA THUMPD3-AS1 promotes invasion and EMT in gastric cancer by regulating the miR-1297/BCAT1 pathwaySemantic proximity Read ↗

DNA methyltransferase 3A isoform b contributes to repressing E-cadherin through cooperation of DNA methylation and H3K27/H3K9 methylation in EMT-related metastasis of gastric cancerSemantic proximity Read ↗

Investigating MATN3 and ASPN as novel drivers of gastric cancer progression via EMT pathwaysSemantic proximity Read ↗

BMP4 promotes the metastasis of gastric cancer by inducing epithelial–mesenchymal transition via ID1Semantic proximity Read ↗

Oxysterol binding protein-like 3 (OSBPL3) is a novel driver gene that promotes tumor growth in part through R-Ras/Akt signaling in gastric cancerSemantic proximity Read ↗

PLOD3 is Upregulated in Gastric Cancer and Correlated with Clinicopathologic CharacteristicsSemantic proximity Read ↗

PAFAH1B3 Expression Is Correlated With Gastric Cancer Cell Proliferation and Immune InfiltrationSemantic proximity Read ↗

The m6A reader IGF2BP3 Facilitates Gastric Cancer Progression Through Activating EMT via Upregulating MYC mRNA StabilitySemantic proximity Read ↗

Overexpression of MATN3 predicts poor prognosis of gastric adenocarcinoma: based on TCGA databaseSemantic proximity Read ↗

MYBL2 promotes cell proliferation and inhibits cell apoptosis via PI3K/AKT and BCL2/BAX/Cleaved-caspase-3 signaling pathway in gastric cancer cellsSemantic proximity Read ↗

Dynamin 3 Gene as a Tumor Suppressor and an Independent Predictive Factor of Poor Prognosis in Patients with Gastric CancerSemantic proximity Read ↗

Identifcation and Validation of EMT-immune-related Prognostic Biomarkers CMTM3 and LTBP2 in Gastric CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.