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Article

A Brg1-Rme1 circuit in Candida albicans hyphal gene regulation.

mBio - 11 Sept 2024

Kim Min-Ju, Cravener Max, Solis Norma, Filler Scott G, Mitchell Aaron P

Abstract excerpt

Major Candida albicans virulence traits include its ability to make hyphae, to produce a biofilm, and to damage host cells. These traits depend upon expression of hypha-associated genes. A gene expression comparison among clinical isolates suggested that transcription factor Rme1, established by previous studies to be a positive regulator of chlamydospore formation, may also be a negative regulator of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39078139
DOI: 10.1128/mbio.01872-24
PMCID: PMC11389389

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