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Article

Integrated analyses of single-cell transcriptome and Mendelian randomization reveal the protective role of FCRL3 in multiple sclerosis.

Frontiers in immunology - 1 Jan 2024

Yu Kefu, Jiang Ruiqi, Li Ziming, Ren Xiaohui, Jiang Haihui, Zhao Zhigang

Abstract excerpt

Background: Multiple sclerosis (MS) represents a multifaceted autoimmune ailment, prompting the development and widespread utilization of numerous therapeutic interventions. However, extant medications for MS have proven inadequate in mitigating relapses and halting disease progression. Innovative drug targets for preventing multiple sclerosis are still required. The objective of this study is to discover novel...

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Gene Expression Profiling
Genome-Wide Association Study
Mendelian Randomization Analysis
Multiple Sclerosis
Quantitative Trait Loci

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Immunologic

Single-Cell Analysis

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Identifiers

PMID: 39076991
DOI: 10.3389/fimmu.2024.1428962
PMCID: PMC11284051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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