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Article

Quantitative assessment of the nanoanatomy of the contractile vacuole complex in Trypanosoma cruzi.

Life science alliance - 1 Oct 2024

Augusto Ingrid, Girard-Dias Wendell, Schoijet Alejandra, Alonso Guillermo Daniel, Portugal Rodrigo V, de Souza Wanderley, Jimenez Veronica, Miranda Kildare

Abstract excerpt

Trypanosoma cruzi uses various mechanisms to cope with osmotic fluctuations during infection, including the remodeling of organelles such as the contractile vacuole complex (CVC). Little is known about the morphological changes of the CVC during pulsation cycles occurring upon osmotic stress. Here, we investigated the structure-function relationship between the CVC and the flagellar pocket domain where fluid...

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Identifiers

PMID: 39074903
DOI: 10.26508/lsa.202402826
PMCID: PMC11287019

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