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Article

A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi.

eLife - 2 Jul 2021

Dave Noopur, Cetiner Ugur, Arroyo Daniel, Fonbuena Joshua, Tiwari Megna, Barrera Patricia, Lander Noelia, Anishkin Andriy, Sukharev Sergei, Jimenez Veronica

Abstract excerpt

The causative agent of Chagas disease undergoes drastic morphological and biochemical modifications as it passes between hosts and transitions from extracellular to intracellular stages. The osmotic and mechanical aspects of these cellular transformations are not understood. Here we identify and characterize a novel mechanosensitive channel in Trypanosoma cruzi (TcMscS) belonging to the superfamily of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34212856
DOI: 10.7554/eLife.67449
PMCID: PMC8282336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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