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Article

The relationship between inflammatory bowel disease and sarcopenia-related traits: a bidirectional two-sample mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Sun Zhihuang, Liu Guangwei, Xu Jiajia, Zhang Xianyu, Wei Huahua, Wu Guobao, Jiang Jian

Abstract excerpt

Objective: Observational studies have revealed a link between inflammatory bowel disease (IBD) and sarcopenia. However, it remains unclear whether this correlation between IBD and sarcopenia is causal. Methods: The genetic instrumental variables (IVs) associated with IBD and sarcopenia-related traits were derived from publicly available genome-wide association studies. We employed a two-sample bidirectional...

Topics

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Colitis, Ulcerative
Crohn Disease
Genome-Wide Association Study
Hand Strength
Inflammatory Bowel Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39072277
DOI: 10.3389/fendo.2024.1402551
PMCID: PMC11272465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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