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Article

Diagnostic accuracy of ESR1 mutation detection by cell-free DNA in breast cancer: a systematic review and meta-analysis of diagnostic test accuracy.

BMC cancer - 28 Jul 2024

Raei Maedeh, Heydari Keyvan, Tabarestani Mohammad, Razavi Alireza, Mirshafiei Fatemeh, Esmaeily Fatemeh, Taheri Mahsa, Hoseini Aref, Nazari Hojjatollah, Shamshirian Danial, Alizadeh-Navaei Reza

Abstract excerpt

BACKGROUND: Estrogen receptors express in nearly 70% of breast cancers (ER-positive). Estrogen receptor alpha plays a fundamental role as a significant factor in breast cancer progression for the early selection of therapeutic approaches. Accordingly, there has been a surge of attention to non-invasive techniques, including circulating Cell-free DNA (ccfDNA) or Cell-Free DNA (cfDNA), to detect and track ESR1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39069608
DOI: 10.1186/s12885-024-12674-z
PMCID: PMC11283726

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