Article
Role of Exercise Hemodynamics in the Prediction of Pulmonary Arterial Hypertension in BMPR2 Mutation Carriers.
Chest - 1 Nov 2024
Gerges Christian, Beurnier Antoine, Jaïs Xavier, Hervé Philippe, Lau Edmund M T, Girerd Barbara, Günther Sven, Bouchachi Amir, Jevnikar Mitja, Boucly Athénaïs, Bogaard Harm Jan, Simonneau Gérald, Sitbon Olivier, Savale Laurent, Chemla Denis, Humbert Marc, Montani David
Abstract excerpt
BACKGROUND: Exercise hemodynamics are recommended for early detection of pulmonary arterial hypertension (PAH) and have been suggested to be predictive of future development of PAH in high-risk populations such as BMPR2 mutation carriers. However, the optimal exercise hemodynamic screening parameter remains to be determined. Recent data suggest that pulmonary vascular distensibility (α) may serve as a useful...
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