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BMPR2 mutations and endothelial dysfunction in pulmonary arterial hypertension (2017 Grover Conference Series)

9 Mar 2018

Abstract excerpt

Despite the discovery more than 15 years ago that patients with hereditary pulmonary arterial hypertension (HPAH) inherit BMP type 2 receptor ( BMPR2) mutations, it is still unclear how these mutations cause disease. In part, this is attributable to the rarity of HPAH and difficulty obtaining tissue samples from patients with early disease. However, in addition, limitations to the approaches used to study the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29521190
DOI: 10.1177/2045894018765840

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