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Article

Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension.

Circulation - 30 May 2006

Elliott C Gregory, Glissmeyer Eric W, Havlena Gregory T, Carlquist John, McKinney Jason T, Rich Stuart, McGoon Michael D, Scholand Mary Beth, Kim Miryoung, Jensen Robert L, Schmidt Jon W, Ward Kenneth

Abstract excerpt

BACKGROUND: Vasoreactivity tests are fundamental in evaluating pulmonary arterial hypertension (PAH). Mutations of the transforming growth factor-beta type II receptor gene, BMPR2, predispose to the development of pulmonary hypertension and may alter the response to vasodilators. Previous investigations have not examined the relationship of BMPR2 mutations to vasoreactivity. METHODS AND RESULTS: We identified 133...

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Share to Adolescent
Share to Bone Morphogenetic Protein Receptors, Type II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Hypertension, Pulmonary

Share to Sequence Analysis, DNA

Share to Vasoconstriction

Share to Vasodilation

Share to Vasodilator Agents

Source

Identifiers

PMID: 16717148
DOI: 10.1161/CIRCULATIONAHA.105.601930

Genes

BMPR2
PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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