Article
B Cell-activating factor (BAFF): A promising trans-nosographic biomarker of inflammation and autoimmunity in bipolar disorder and schizophrenia.
Brain, behavior, and immunity - 1 Oct 2024
Boukouaci Wahid, Lajnef Mohamed, Wu Ching-Lien, Bouassida Jihène, Saitoh Kaori, Sugunasabesan Sobika, Richard Jean-Romain, Apavou Maud, Lamy Anais, Henensal Adèle, Nkam Irène, Hasty Lauren, Sayous Romain, Bengoufa Djaouida, Barau Caroline, Le Corvoisier Philippe, Honnorat Jérome, Maskos Uwe, Yolken Robert, Leboyer Marion, Tamouza Ryad
Abstract excerpt
Immune dysregulation is an important aspect of schizophrenia (SZ) and bipolar disorders (BD) pathophysiology, including not only inflammatory but also autoimmune process reflective of abnormal humoral immune responses. Given that B cell-activating factor (BAFF) is an integral aspect of B lymphocyte regulation, the current study investigated BAFF in SZ and BD. 255 SZ patients, 407 BD patients and 185 healthy...
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