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Article

Dietary methionine functions in proliferative zone maintenance and egg production via sams-1 in Caenorhabditis elegans.

Journal of biochemistry - 4 Nov 2024

Hirota Keiko, Yamauchi Rieko, Miyata Mai, Kojima Mariko, Kako Koichiro, Fukamizu Akiyoshi

Abstract excerpt

The maintenance of germ cells is critical for the prosperity of offspring. The amount of food consumption is known to be closely related to reproduction, i.e. the number of eggs decreases under calorie-restricted conditions in various organisms. Previous studies in Caenorhabditis elegans have reported that calorie restriction reduces the number of eggs and the reduction can be rescued by methionine. However, the...

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PMID: 39046461
DOI: 10.1093/jb/mvae054

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