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Therapeutic efficacy of pyronaridine-artesunate (Pyramax) in treating Plasmodium vivax malaria in the central highlands of Vietnam.

Antimicrobial agents and chemotherapy - 4 Sept 2024

Manh Nguyen Duc, Thanh Nguyen Van, Quang Huynh Hong, Van Nguyen Thi Thanh, San Nguyen Ngoc, Phong Nguen Chinh, Birrell Geoffrey W, Edgel Kimberly A, Martin Nicholas J, Edstein Michael D, Chavchich Marina

Abstract excerpt

The emergence and spread of chloroquine-resistant Plasmodium vivax have necessitated the assessment of alternative blood schizonticidal drugs. In Vietnam, chloroquine-resistant P. vivax malaria has been reported. In an open-label, single-arm trial, the safety, tolerability, and efficacy of pyronaridine-artesunate (Pyramax, PA) was evaluated in Dak Nong province, Vietnam. A 3-day course of PA was administered to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39046237
DOI: 10.1128/aac.00044-24
PMCID: PMC11373200

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