Article
Association of RAN and RANBP2 Gene Polymorphisms With Glioma Susceptibility in Chinese Children.
Cancer reports (Hoboken, N.J.) - 1 Jul 2024
Lin Qianru, Chen Wei, Tan Jiating, Qian Sifan, Su Huarong, Zhao Liang, Yuan Li, Ruan Jichen, Huang Xiaokai, Zhou Haixia
Abstract excerpt
BACKGROUND: Glioma is the most prevalent pediatric central nervous system malignancy. RAN, member RAS oncogene family (RAN), is a key signaling molecule that regulates the polymerization of microtubules during mitosis. RAN binding protein 2 (RANBP2) is involved in DNA replication, mitosis, metabolism, and tumorigenesis. The effects of RAN and RANBP2 gene polymorphisms on glioma susceptibility in Chinese children...
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