Article
A Systematic Review and Meta-Analysis for the Association of Gene Polymorphisms in RAN with Cancer Risk.
Disease markers - 1 Jan 2020
Li Yanke, Zhang Fuqiang, Xing Chengzhong
Abstract excerpt
As an important component of miRNA processing genes, RAN gene encodes the ras-related nuclear protein, which is a unique member of the Ras superfamily of GTPases. The mutations in RAN gene are very likely to play a critical role in pathology-related changes to miRNA transport and expression and thus participate in tumor genesis and development. Currently, accumulating studies have explored the association between...
Topics
- Humans
- Neoplasms
- Polymorphism, Single Nucleotide
- ran GTP-Binding Protein